The degree in Industrial and Systems Engineering was born as a response to the requirements for capable professionals who can direct optimization and improve the productive processes under the criteria of quality, security and safety and respect for the environment.

In August 1994 the first study plan was implemented for this degree. The main areas of knowledge are: Basic Sciences, Mechanics and Manufacturing, Production and Industrial Management, Industrial Processes and Analysis and Optimization of Systems. In the 3rd version of the study plan, still in place, improvements and updates have been incorporated in the contents and outlook of the program for this degree.

During the period of 2004-2005, the Industrial and Systems Engineering degree within its framework of Experimental Mechanism of Accreditation MEXA-MERCOSUR, was submitted to a process of self-evaluation and accreditation. The process of self-evaluation was carried out based on criteria in academic quality of academic programs in Engineering, established by academic authorities of the countries conforming the MERCOSUR. The process culminated with the preparation of a report that allowed the degree of Industrial and Systems Engineering of UPSA to be elected as one of the best seven programs in Engineering in Bolivia and obtaining the corresponding accreditation.